N27K (p.Asn27Lys) variant of ARAF (P10398)
N27K (p.Asn27Lys) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
N27K (p.Asn27Lys) variant details
- p.Asn27Lys
- gnomAD X-47563048-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.556
- REVEL 0.70
- CADD 24.80
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.0457
- Literature evidence available