G19C (p.Gly19Cys) variant of ARAF (P10398)
G19C (p.Gly19Cys) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G19C (p.Gly19Cys) variant details
- p.Gly19Cys
- gnomAD X-47563022-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.624
- REVEL 0.56
- CADD 25.80
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.352
- Literature evidence available