G19A (p.Gly19Ala) variant of ARAF (P10398)
G19A (p.Gly19Ala) in ARAF (P10398) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G19A (p.Gly19Ala) variant details
- p.Gly19Ala
- gnomAD X-47563020-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.551
- CADD 23.60
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.352
- Literature evidence available