G11G (p.Gly11Gly) variant of ARAF (P10398)
G11G (p.Gly11Gly) in ARAF (P10398) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
G11G (p.Gly11Gly) variant details
- p.Gly11Gly
- rs761115487
- gnomAD X-47563000-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.427
- CADD 12.10
- Most common in the South Asian population (allele frequency 0.00039)
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.35
- Literature evidence available