E2D (p.Glu2Asp) variant of ARAF (P10398)
E2D (p.Glu2Asp) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E2D (p.Glu2Asp) variant details
- p.Glu2Asp
- Ensembl rs2147902422
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.14
- CADD 17.00
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.312