E13D (p.Glu13Asp) variant of ARAF (P10398)
E13D (p.Glu13Asp) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, and structural context.
E13D (p.Glu13Asp) variant details
- p.Glu13Asp
- Ensembl rs1603042042
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.25
- CADD 9.46
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.856