D37G (p.Asp37Gly) variant of ARAF (P10398)
D37G (p.Asp37Gly) in ARAF (P10398) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D37G (p.Asp37Gly) variant details
- p.Asp37Gly
- gnomAD X-47563239-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.35
- CADD 23.00
- PolyPhen-2 0.14
- SIFT 0.20
- Population evidence available
- Structural context available
- ARAF Raf-like Ras-binding domain domainome 1.0: score -0.408
- Literature evidence available