G77V (p.Gly77Val) variant of AQP7 (Aquaporin-7)
G77V (p.Gly77Val) in AQP7 (Aquaporin-7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G77V (p.Gly77Val) variant details
- p.Gly77Val
- cosmic curated COSV53037
- Ensembl rs1354676296
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.22
- CADD 22.80
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00022)
- Structural context available