F37L (p.Phe37Leu) variant of AQP7 (Aquaporin-7)
F37L (p.Phe37Leu) in AQP7 (Aquaporin-7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F37L (p.Phe37Leu) variant details
- p.Phe37Leu
- TOPMed rs1170273419
- gnomAD rs1170273419
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.16
- CADD 20.40
- PolyPhen-2 0.07
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available