Q86P (p.Gln86Pro) variant of AQP4 (Aquaporin-4)
Q86P (p.Gln86Pro) in AQP4 (Aquaporin-4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
Q86P (p.Gln86Pro) variant details
- p.Gln86Pro
- gnomAD rs1461680936
- Missense
- Variant Prioritization Score for Impact Estimate 0.799
- REVEL 0.92
- CADD 25.90
- PolyPhen-2 0.66
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available