F35Y (p.Phe35Tyr) variant of AQP1 (Aquaporin-1)
F35Y (p.Phe35Tyr) in AQP1 (Aquaporin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
F35Y (p.Phe35Tyr) variant details
- p.Phe35Tyr
- TOPMed rs1408614489
- gnomAD rs1408614489
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.27
- MetaLR 0.37
- MetaSVM -0.52
- CADD 22.90
- PolyPhen-2 0.21
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available