W13R (p.Trp13Arg) variant of APP (Amyloid-beta precursor protein)
W13R (p.Trp13Arg) in APP (Amyloid-beta precursor protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
W13R (p.Trp13Arg) variant details
- p.Trp13Arg
- TOPMed rs1206506558
- gnomAD rs1206506558
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.41
- CADD 23.40
- PolyPhen-2 0.00
- SIFT 0.33
- Population evidence available
- Structural context available