Y115S (p.Tyr115Ser) variant of APOH (Beta-2-glycoprotein 1)
Y115S (p.Tyr115Ser) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
Y115S (p.Tyr115Ser) variant details
- p.Tyr115Ser
- ExAC rs748274839
- gnomAD rs748274839
- Missense
- Variant Prioritization Score for Impact Estimate 0.435
- REVEL 0.24
- CADD 15.30
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available