S11T (p.Ser11Thr) variant of APOH (Beta-2-glycoprotein 1)
S11T (p.Ser11Thr) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
S11T (p.Ser11Thr) variant details
- p.Ser11Thr
- TOPMed rs907406873
- gnomAD rs907406873
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.05
- CADD 5.64
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available