R58P (p.Arg58Pro) variant of APOH (Beta-2-glycoprotein 1)
R58P (p.Arg58Pro) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R58P (p.Arg58Pro) variant details
- p.Arg58Pro
- ExAC rs768884547
- TOPMed rs768884547
- gnomAD rs768884547
- Missense
- Variant Prioritization Score for Impact Estimate 0.491
- REVEL 0.36
- CADD 22.00
- PolyPhen-2 0.48
- SIFT 0.02
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available