R21P (p.Arg21Pro) variant of APOH (Beta-2-glycoprotein 1)
R21P (p.Arg21Pro) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R21P (p.Arg21Pro) variant details
- p.Arg21Pro
- ESP rs149659675
- ExAC rs149659675
- TOPMed rs149659675
- gnomAD rs149659675
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.21
- CADD 14.50
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available