L77V (p.Leu77Val) variant of APOH (Beta-2-glycoprotein 1)
L77V (p.Leu77Val) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L77V (p.Leu77Val) variant details
- p.Leu77Val
- ExAC rs1803124
- gnomAD rs1803124
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.08
- CADD 18.20
- PolyPhen-2 0.03
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available