L77P (p.Leu77Pro) variant of APOH (Beta-2-glycoprotein 1)
L77P (p.Leu77Pro) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
L77P (p.Leu77Pro) variant details
- p.Leu77Pro
- TOPMed rs1368050083
- Missense
- Variant Prioritization Score for Impact Estimate 0.386
- REVEL 0.22
- CADD 24.60
- PolyPhen-2 0.29
- SIFT 0.02
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available