L71M (p.Leu71Met) variant of APOH (Beta-2-glycoprotein 1)
L71M (p.Leu71Met) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
L71M (p.Leu71Met) variant details
- p.Leu71Met
- TOPMed rs780689357
- gnomAD rs780689357
- Missense
- Variant Prioritization Score for Impact Estimate 0.0735
- REVEL 0.09
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available