K123R (p.Lys123Arg) variant of APOH (Beta-2-glycoprotein 1)
K123R (p.Lys123Arg) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
K123R (p.Lys123Arg) variant details
- p.Lys123Arg
- ExAC rs766663087
- TOPMed rs766663087
- gnomAD rs766663087
- Missense
- Variant Prioritization Score for Impact Estimate 0.065
- REVEL 0.04
- CADD 5.40
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available