I74V (p.Ile74Val) variant of APOH (Beta-2-glycoprotein 1)
I74V (p.Ile74Val) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
I74V (p.Ile74Val) variant details
- p.Ile74Val
- TOPMed rs1369699001
- gnomAD rs1369699001
- Missense
- Variant Prioritization Score for Impact Estimate 0.0446
- REVEL 0.03
- CADD 0.54
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available