F86L (p.Phe86Leu) variant of APOH (Beta-2-glycoprotein 1)
F86L (p.Phe86Leu) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
F86L (p.Phe86Leu) variant details
- p.Phe86Leu
- ExAC rs777314989
- gnomAD rs777314989
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.20
- CADD 23.10
- PolyPhen-2 0.03
- SIFT 0.24
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available