F64C (p.Phe64Cys) variant of APOH (Beta-2-glycoprotein 1)
F64C (p.Phe64Cys) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
F64C (p.Phe64Cys) variant details
- p.Phe64Cys
- ESP rs368674146
- ExAC rs368674146
- TOPMed rs368674146
- gnomAD rs368674146
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.40
- CADD 23.90
- PolyPhen-2 0.90
- SIFT 0.01
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available