F108V (p.Phe108Val) variant of APOH (Beta-2-glycoprotein 1)
F108V (p.Phe108Val) in APOH (Beta-2-glycoprotein 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
F108V (p.Phe108Val) variant details
- p.Phe108Val
- gnomAD rs1258002112
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- REVEL 0.53
- CADD 26.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available