W52L (p.Trp52Leu) variant of APOE (Apolipoprotein E)
W52L (p.Trp52Leu) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
W52L (p.Trp52Leu) variant details
- p.Trp52Leu
- gnomAD 19-44907871-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.56
- CADD 25.20
- PolyPhen-2 0.96
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available