W38L (p.Trp38Leu) variant of APOE (Apolipoprotein E)
W38L (p.Trp38Leu) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
W38L (p.Trp38Leu) variant details
- p.Trp38Leu
- TOPMed rs1301411037
- gnomAD rs1301411037
- Missense
- Variant Prioritization Score for Impact Estimate 0.251
- REVEL 0.19
- CADD 20.00
- PolyPhen-2 0.21
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available