V24M (p.Val24Met) variant of APOE (Apolipoprotein E)
V24M (p.Val24Met) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
V24M (p.Val24Met) variant details
- p.Val24Met
- TOPMed rs1394832846
- gnomAD rs1394832846
- Missense
- Variant Prioritization Score for Impact Estimate 0.172
- REVEL 0.25
- CADD 2.61
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available