V10I (p.Val10Ile) variant of APOE (Apolipoprotein E)
V10I (p.Val10Ile) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
V10I (p.Val10Ile) variant details
- p.Val10Ile
- gnomAD rs1461741495
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.32
- CADD 14.30
- PolyPhen-2 0.08
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available