T11P (p.Thr11Pro) variant of APOE (Apolipoprotein E)
T11P (p.Thr11Pro) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
T11P (p.Thr11Pro) variant details
- p.Thr11Pro
- gnomAD 19-44906655-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.51
- CADD 7.75
- PolyPhen-2 0.09
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available
- Literature evidence available