S40T (p.Ser40Thr) variant of APOE (Apolipoprotein E)

Name: APOE S40T (p.Ser40Thr) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-10
License: https://catvariant.com/terms-of-use

S40T (p.Ser40Thr) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.

S40T (p.Ser40Thr) variant details

p.Ser40Thr
rs1233347077
gnomAD 19-44905894-G-C
Missense
Variant Prioritization Score for Impact Estimate 0.129
CADD 6.80
Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
Structural context available
Literature evidence available