Q35R (p.Gln35Arg) variant of APOE (Apolipoprotein E)
Q35R (p.Gln35Arg) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
Q35R (p.Gln35Arg) variant details
- p.Gln35Arg
- gnomAD rs1249808975
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.39
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available