Q34P (p.Gln34Pro) variant of APOE (Apolipoprotein E)
Q34P (p.Gln34Pro) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
Q34P (p.Gln34Pro) variant details
- p.Gln34Pro
- gnomAD 19-44907817-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.29
- CADD 3.68
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available
- Literature evidence available