P28S (p.Pro28Ser) variant of APOE (Apolipoprotein E)
P28S (p.Pro28Ser) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P28S (p.Pro28Ser) variant details
- p.Pro28Ser
- gnomAD rs1969835176
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.17
- CADD 0.09
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available