L13R (p.Leu13Arg) variant of APOE (Apolipoprotein E)
L13R (p.Leu13Arg) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
L13R (p.Leu13Arg) variant details
- p.Leu13Arg
- Ensembl rs1568615443
- Missense
- Variant Prioritization Score for Impact Estimate 0.723
- REVEL 0.77
- CADD 29.20
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available