G41V (p.Gly41Val) variant of APOE (Apolipoprotein E)
G41V (p.Gly41Val) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G41V (p.Gly41Val) variant details
- p.Gly41Val
- gnomAD 19-44907838-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.37
- CADD 14.50
- PolyPhen-2 0.26
- SIFT 0.02
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available
- Literature evidence available