F51I (p.Phe51Ile) variant of APOE (Apolipoprotein E)
F51I (p.Phe51Ile) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
F51I (p.Phe51Ile) variant details
- p.Phe51Ile
- gnomAD 19-44907867-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.508
- REVEL 0.57
- CADD 23.20
- PolyPhen-2 0.81
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available