A23V (p.Ala23Val) variant of APOE (Apolipoprotein E)
A23V (p.Ala23Val) in APOE (Apolipoprotein E) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A23V (p.Ala23Val) variant details
- p.Ala23Val
- ExAC rs776242156
- TOPMed rs776242156
- gnomAD rs776242156
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.34
- CADD 0.05
- PolyPhen-2 0.00
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available