S27P (p.Ser27Pro) variant of APOC3 (Apolipoprotein C-III)
S27P (p.Ser27Pro) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
S27P (p.Ser27Pro) variant details
- p.Ser27Pro
- ExAC rs745663150
- gnomAD rs745663150
- Missense
- Variant Prioritization Score for Impact Estimate 0.585
- REVEL 0.45
- CADD 21.90
- PolyPhen-2 0.97
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available