R60G (p.Arg60Gly) variant of APOC3 (Apolipoprotein C-III)
R60G (p.Arg60Gly) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
R60G (p.Arg60Gly) variant details
- p.Arg60Gly
- gnomAD 11-116830895-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- REVEL 0.76
- CADD 35.00
- PolyPhen-2 0.74
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available