R4Q (p.Arg4Gln) variant of APOC3 (Apolipoprotein C-III)
R4Q (p.Arg4Gln) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R4Q (p.Arg4Gln) variant details
- p.Arg4Gln
- ExAC rs779597455
- TOPMed rs779597455
- gnomAD rs779597455
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- REVEL 0.34
- CADD 21.50
- PolyPhen-2 0.02
- SIFT 0.08
- Most common in the Middle Eastern population (allele frequency 0.00035)
- Structural context available