P3S (p.Pro3Ser) variant of APOC3 (Apolipoprotein C-III)
P3S (p.Pro3Ser) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
P3S (p.Pro3Ser) variant details
- p.Pro3Ser
- ExAC rs777982400
- gnomAD rs777982400
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.23
- CADD 14.00
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the South Asian population (allele frequency 0.00013)
- Structural context available