L6F (p.Leu6Phe) variant of APOC3 (Apolipoprotein C-III)
L6F (p.Leu6Phe) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L6F (p.Leu6Phe) variant details
- p.Leu6Phe
- TOPMed rs897724132
- gnomAD rs897724132
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.15
- CADD 9.21
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available