K37R (p.Lys37Arg) variant of APOC3 (Apolipoprotein C-III)
K37R (p.Lys37Arg) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K37R (p.Lys37Arg) variant details
- p.Lys37Arg
- TOPMed rs1294710674
- gnomAD rs1294710674
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.25
- CADD 22.80
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available