G66S (p.Gly66Ser) variant of APOC3 (Apolipoprotein C-III)
G66S (p.Gly66Ser) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
G66S (p.Gly66Ser) variant details
- p.Gly66Ser
- gnomAD rs1395523362
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.16
- CADD 0.42
- PolyPhen-2 0.05
- SIFT 0.54
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available