D25Y (p.Asp25Tyr) variant of APOC3 (Apolipoprotein C-III)
D25Y (p.Asp25Tyr) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
D25Y (p.Asp25Tyr) variant details
- p.Asp25Tyr
- gnomAD rs1475121895
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.38
- CADD 25.70
- PolyPhen-2 0.77
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available