A46T (p.Ala46Thr) variant of APOC3 (Apolipoprotein C-III)
A46T (p.Ala46Thr) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
A46T (p.Ala46Thr) variant details
- p.Ala46Thr
- Ensembl rs1941438812
- Missense
- Variant Prioritization Score for Impact Estimate 0.38
- REVEL 0.19
- CADD 13.50
- PolyPhen-2 0.12
- SIFT 0.14
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available