A23T (p.Ala23Thr) variant of APOC3 (Apolipoprotein C-III)
A23T (p.Ala23Thr) in APOC3 (Apolipoprotein C-III) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A23T (p.Ala23Thr) variant details
- p.Ala23Thr
- gnomAD rs1261591521
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.18
- CADD 7.61
- PolyPhen-2 0.04
- SIFT 0.32
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available