T21S (p.Thr21Ser) variant of APOA5 (Apolipoprotein A-V)
T21S (p.Thr21Ser) in APOA5 (Apolipoprotein A-V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T21S (p.Thr21Ser) variant details
- p.Thr21Ser
- TOPMed rs1312280193
- gnomAD rs1312280193
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.05
- CADD 6.50
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available