Q22R (p.Gln22Arg) variant of APOA5 (Apolipoprotein A-V)
Q22R (p.Gln22Arg) in APOA5 (Apolipoprotein A-V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
Q22R (p.Gln22Arg) variant details
- p.Gln22Arg
- TOPMed rs1459532692
- gnomAD rs1459532692
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.28
- CADD 21.40
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available