L74M (p.Leu74Met) variant of APOA5 (Apolipoprotein A-V)
L74M (p.Leu74Met) in APOA5 (Apolipoprotein A-V) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
L74M (p.Leu74Met) variant details
- p.Leu74Met
- gnomAD rs1229786953
- Missense
- Variant Prioritization Score for Impact Estimate 0.582
- REVEL 0.51
- CADD 23.10
- PolyPhen-2 0.71
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available